PP2A Cancerous-IN-1

PP2A Cancerous-IN-1

• CAS Number: 1403933-79-8
• UNSPSC Description: PP2A Cancerous-IN-1 is a strong and potent CIP2A (Cancerous inhibitor of PP2A) and p-Akt inhibitor. PP2A Cancerous-IN-1 shows the most potent antiproliferative activities[1]. PP2A Cancerous-IN-1 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
• Target Antigen: Akt
• Type: Reference compound
• Related Pathways: PI3K/Akt/mTOR
• Applications: Cancer-Kinase/protease
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/pp2a-cancerous-in-1.html
• Solubility: 10 mM in DMSO
• Smiles: C#CC1=CC=CC(NC2=C3C=C(OC)C(OC)=CC3=NC(NC4=CC=C(C=C4)OC5=CC=CC=C5)=N2)=C1
• Molecular Weight: 488.54
• References & Citations: [1]Chen KF, et al. Development of erlotinib derivatives as CIP2A-ablating agents independent of EGFR activity. Bioorg Med Chem. 2012;20(20):6144-6153.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported