Thalidomide-4-O-C5-NH2

CAT:

804-HY-138848

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CAS Number: 2307477-23-0
UNSPSC Description: Thalidomide-4-O-C5-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology[1].
Target Antigen: Apoptosis; Autophagy; E3 Ligase Ligand-Linker Conjugates
Type: Reference compound
Related Pathways: Apoptosis;Autophagy;PROTAC
Applications: Cancer-programmed cell death
Field of Research: Cancer
Assay Protocol: https://www.medchemexpress.com/thalidomide-4-o-c5-nh2.html
Solubility: 10 mM in DMSO
Smiles: O=C1N(C(CC2)C(NC2=O)=O)C(C3=C1C=CC=C3OCCCCCN)=O
Molecular Weight: 359.38
References & Citations: [1]Sato T, et al. Cereblon-Based Small-Molecule Compounds to Control Neural Stem Cell Proliferation in Regenerative Medicine. Front Cell Dev Biol. 2021;9:629326. Published 2021 Mar 11.|[2]Nalawansha DA, et al. PROTACs: An Emerging Therapeutic Modality in Precision Medicine. Cell Chem Biol. 2020;27(8):998-985.
Shipping Conditions: Room temperature
Clinical Information: No Development Reported

Cat	Name
HY-138848	Thalidomide-4-O-C5-NH2
HY-138848A-02	Thalidomide-4-O-C5-NH2 (hydrochloride)
HY-138848A-01	Thalidomide-4-O-C5-NH2 (hydrochloride)
HY-138848A-03	Thalidomide-4-O-C5-NH2 (hydrochloride)
HY-141423-01	Thalidomide-O-amide-C5-NH2
HY-141423-02	Thalidomide-O-amide-C5-NH2
HY-149562-01	Thalidomide-5-O-C5-NH2 (hydrochloride)
HY-149562-02	Thalidomide-5-O-C5-NH2 (hydrochloride)
HY-141423A	Thalidomide-O-amide-C5-NH2 (TFA)
HY-134986	Thalidomide-NH-C5-NH2

Cat	Name
T39900-5mg	Thalidomide-O-amide-C5-NH2
T40079-10mg	Thalidomide-O-C5-NH2 hydrochloride
T39900-50mg	Thalidomide-O-amide-C5-NH2
T40079-1g	Thalidomide-O-C5-NH2 hydrochloride
MBS5800391	Thalidomide-O-C5-NH2 hydrochloride
T39900-1mg	Thalidomide-O-amide-C5-NH2
T40079-1mg	Thalidomide-O-C5-NH2 hydrochloride
T40079-5mg	Thalidomide-O-C5-NH2 hydrochloride
T39900-10mg	Thalidomide-O-amide-C5-NH2
MBS5800280-01	Thalidomide-O-amide-C5-NH2