DGTP

• Description :

  DGTP (2'-Deoxyguanosine-5'-triphosphate), a guanosine nucleotide, can be used in deoxyribonucleic acid synthesis. Guanosine nucleotides (GDP, GTP, dGDP, and dGTP) are highly susceptible to oxidative damage to 8-oxo-GDP (8-O-GDP), 8-O-dGTP, 8-O-GTP, and 8-O-dGTP[1].

• Product Name Alternative :

  2'-Deoxyguanosine-5'-triphosphate

• UNSPSC :

  12352005

• Hazard Statement :

  H302-H315-H319-H335

• Target :

  DNA/RNA Synthesis; Nucleoside Antimetabolite/Analog

• Type :

  Oligonucleotides

• Related Pathways :

  Cell Cycle/DNA Damage

• Applications :

  COVID-19-anti-virus

• Field of Research :

  Cancer; Infection

• Assay Protocol :

  https://www.medchemexpress.com/dgtp.html

• Solubility :

  10 mM in DMSO

• Smiles :

  O[C@H]1C[C@H](N2C(N=C(N)NC3=O)=C3N=C2)O[C@@H]1COP(OP(OP(O)(O)=O)(O)=O)(O)=O

• Molecular Formula :

  C10H16N5O13P3

• Molecular Weight :

  507.18

• Precautions :

  P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

• References & Citations :

  [1]Kapoor I, et al. Nucleoside Diphosphate Kinase Escalates A-to-C Mutations in MutT-Deficient Strains of Escherichia coli. J Bacteriol. 2019;202 (1) :e00567-19. Published 2019 Dec 6.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Oligonucleotides

• Clinical Information :

  No Development Reported

• CAS Number :

  [2564-35-4]