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Obafluorin

CAT: 0804-HY-138075Size: 500 µgDry Ice: NoHazardous: No
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CAT#:0804-HY-138075Size:500 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Obafluorin is a β-Lactone Antibiotic, that can be produced by Pseudomonas fluorescens ATCC 39502. Obafluorin exhibits antibacterial activity against a range of Gram-positive and Gram-negative bacteria. Obafluorin fully inhibits E. coli threonyl-tRNA synthetase[1].
CAS Number
92121-68-1
UNSPSC
12352005
Target
Antibiotic; Bacterial
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/obafluorin.html
Solubility
10 mM in DMSO
Smiles
O=C(C(C=CC=C1O)=C1O)N[C@H](C2=O)[C@H](O2)CC(C=C3)=CC=C3[N](=O)=O
Molecular Formula
C17H14N2O7
Molecular Weight
358.30
References & Citations
[1]Scott TA, et al. Immunity-Guided Identification of Threonyl-tRNA Synthetase as the Molecular Target of Obafluorin, a β-Lactone Antibiotic. ACS Chem Biol. 2019 Dec 20;14 (12) :2663-2671.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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