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Ranimustine

CAT: 0804-HY-13739-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-13739-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Ranimustine (MCNU) is a nitrosourea alkylating agent, can be used for research of chronic myelogenous leukemia and polycythemia vera[1][3][4].
CAS Number
58994-96-0
Product Name Alternative
MCNU
UNSPSC
12352005
Target
DNA Alkylator/Crosslinker
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/ranimustine.html
Solubility
10 mM in DMSO
Smiles
O[C@H]1[C@@H](OC)O[C@H](CNC(N(CCCl)N=O)=O)[C@@H](O)[C@@H]1O
Molecular Formula
C10H18ClN3O7
Molecular Weight
327.72
References & Citations
[1]Kameoka Y, et al. Safety and efficacy of high-dose ranimustine (MCNU) containing regimen followed by autologous stem cell transplantation for diffuse large B-cell lymphoma. Int J Hematol. 2018 Nov;108 (5) :510-515. |[2]Watanabe S, et al. Chemotherapeutic choice of ranimustine or nimustine on the basis of regional polyamine levels in rat brain. Methods Find Exp Clin Pharmacol. 2008 Mar;30 (2) :115-20. |[3]Kitajima K, et al. [Chemotherapy of chronic myelogenous leukemia--VP (M) regimen initiated during its chronic phase, and evaluation of MCNU in the phase of blastic crisis]. Gan To Kagaku Ryoho. 1989 Nov;16 (11) :3573-9. Japanese. |[4]Nagai M, et al. [Therapeutic effect of ranimustine (MCNU) on essential thrombocythemia and polycythemia vera]. Gan To Kagaku Ryoho. 1988 Dec;15 (12) :3267-70. Japanese.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Alternative Products

CatalogName
TRC-R120030-25MGRanimustine

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