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Procarbazine

CAT: 0804-HY-13733ASize: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-13733ASize:1 Each
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Description
Procarbazine is an orally active alkylating agent, with anticancer activity. Procarbazine can be used in Hodgkin's disease research[1][2].
CAS Number
671-16-9
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335-H351-H361
Target
DNA Alkylator/Crosslinker
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/procarbazine.html
Solubility
10 mM in DMSO
Smiles
O=C(NC(C)C)C1=CC=C(CNNC)C=C1
Molecular Formula
C12H19N3O
Molecular Weight
221.30
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
References & Citations
[1]J M Erikson, et al. Cytotoxicity and DNA damage caused by the azoxy metabolites of procarbazine in L1210 tumor cells. Cancer Res. 1989 Jan 1;49 (1) :127-33.|[2]T Suzuki, et al. Procarbazine genotoxicity in the MutaMouse; strong clastogenicity and organ-specific induction of lacZ mutations. Mutat Res. 1999 Aug 18;444 (2) :269-81.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Launched

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