Trifluoperazine N-glucuronide-d3

Trifluoperazine N-glucuronide-d3

• UNSPSC Description: Trifluoperazine N-glucuronide-d3 is deuterium labeled Trifluoperazine N-Glucuronide. Trifluoperazine N-Glucuronide (UGT1A4), as one of the human UGT1A isoforms, is expressed in the liver. Trifluoperazine N-Glucuronide catalyzes the imipramine and trifluoperazine Nglucuronide formation[1].
• Target Antigen: Isotope-Labeled Compounds
• Type: Isotope-Labeled Compounds
• Related Pathways: Others
• Applications: Metabolism-protein/nucleotide metabolism
• Field of Research: Metabolic Disease
• Purity: 93.0
• Solubility: 10 mM in DMSO
• Smiles: O=C([C@@H]1[C@@H](O)[C@H](O)[C@@H](O)[C@H]([N+]2(C([2H])([2H])[2H])CCN(CCCN3C4=C(C=CC=C4)SC5=CC=C(C(F)(F)F)C=C35)CC2)O1)[O-]
• Molecular Weight: 586.64
• References & Citations: [1]Fujiwara R, et al. Interactions between human UGT1A1, UGT1A4, and UGT1A6 affect their enzymatic activities. Drug Metab Dispos. 2007;35(10):1781-1787|[2]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.
• Shipping Conditions: Blue Ice
• Storage Conditions: -20°C, 3 years (Powder)
• Clinical Information: No Development Reported