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Trifluoperazine N-glucuronide-d3

CAT: 0804-HY-137083SSize: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-137083SSize:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Trifluoperazine N-glucuronide-d3 is deuterium labeled Trifluoperazine N-Glucuronide. Trifluoperazine N-Glucuronide (UGT1A4), as one of the human UGT1A isoforms, is expressed in the liver. Trifluoperazine N-Glucuronide catalyzes the imipramine and trifluoperazine Nglucuronide formation[1].
Product Name Alternative
UGT1A4-d3
UNSPSC
12352005
Target
Isotope-Labeled Compounds
Type
Isotope-Labeled Compounds
Related Pathways
Others
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Purity
93.87
Solubility
10 mM in DMSO
Smiles
O=C([C@@H]1[C@@H](O)[C@H](O)[C@@H](O)[C@H]([N+]2(C([2H])([2H])[2H])CCN(CCCN3C4=C(C=CC=C4)SC5=CC=C(C(F)(F)F)C=C35)CC2)O1)[O-]
Molecular Formula
C27H29D3F3N3O6S
Molecular Weight
586.64
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216.|[2]Fujiwara R, et al. Interactions between human UGT1A1, UGT1A4, and UGT1A6 affect their enzymatic activities. Drug Metab Dispos. 2007;35 (10) :1781-1787
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported