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Gitoxin

CAT:
804-HY-136933
Size:
5 mg
Price:
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For price, please contact [email protected]
  • Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
  • Dry Ice Shipment: No
Gitoxin - image 1

Gitoxin

  • CAS Number: 4562-36-1
  • UNSPSC Description: Gitoxin, a Na+/K+-ATPase inhibitor, usually appears as a result of metabolic degradation of Digitoxin, is just the hydroxyl (ZOH) group close to the C-17β position, which changes the pharmacokinetics and pharmacodynamics of these substances considerably[1].
  • Target Antigen: Na+/K+ ATPase
  • Type: Natural Products
  • Related Pathways: Membrane Transporter/Ion Channel
  • Applications: Neuroscience-Neuromodulation
  • Field of Research: Cardiovascular Disease
  • Assay Protocol: https://www.medchemexpress.com/gitoxin.html
  • Purity: 95.0
  • Solubility: Ethanol : 8 mg/mL (ultrasonic;warming)
  • Smiles: O[C@@]([C@@]([C@@]1([H])C(CO2)=CC2=O)(CC3)C)(C[C@@H]1O)[C@@](CC[C@]4([H])C[C@H]5O[C@H](O[C@@H]6C)C[C@@H]([C@@H]6O[C@H](O[C@@H]7C)C[C@@H]([C@@H]7O[C@H](O[C@@H]8C)C[C@@H]([C@@H]8O)O)O)O)([H])[C@@]3([H])[C@]4(CC5)C
  • Molecular Weight: 780.94
  • References & Citations: [1]Danijela Krstić, et al. Effects of digoxin and gitoxin on the enzymatic activity and kinetic parameters of Na+/K+-ATPase. J Enzyme Inhib Med Chem. 2004 Oct;19(5):409-15.
  • Shipping Conditions: Room Temperature
  • Storage Conditions: -20°C, 3 years; 4°C, 2 years (Powder)
  • Clinical Information: No Development Reported