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Flufylline

CAT: 0804-HY-136880Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-136880Size:1 Each
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Description
Flufylline shows antihypertensive properties in spontaneously hypertensive rats and display antagonism towards 5-HT receptors in various animal models. Flufylline can be used for cardiovascular disease research[1].
CAS Number
82190-91-8
Product Name Alternative
Sgd 195/78
UNSPSC
12352005
Target
5-HT Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/flufylline.html
Solubility
10 mM in DMSO
Smiles
O=C1C2=C(N(C)C(N1C)=O)N=CN2CCN3CCC(CC3)C(C4=CC=C(C=C4)F)=O
Molecular Formula
C21H24FN5O3
Molecular Weight
413.45
References & Citations
[1]Korstanje C, et al. Characterization of flufylline, fluprofylline, ritanserin, butanserin and R 56413 with respect to in-vivo alpha 1-, alpha 2- and 5-HT2-receptor antagonism and in-vitro affinity for alpha 1-, alpha 2- and 5-HT2-receptors: comparison with ketanserin. J Pharm Pharmacol. 1986 May;38 (5) :374-9.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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CatalogName
450143-01Flufylline

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