IDH-C227

• Description:

  IDH-C227 is a potent and selective IDH1R132H inhibitor. IDH-C227 has anticancer effcts[1].

• UNSPSC:

  12352005

• Target:

  Isocitrate Dehydrogenase (IDH)

• Type:

  Reference compound

• Related Pathways:

  Metabolic Enzyme/Protease

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/idh-c227.html

• Solubility:

  10 mM in DMSO

• Smiles:

  N#CC1=CC=C (NCC (N (C (C2=C (C) C=CC=C2) C (NC3CCCCC3) =O) C4=CC (F) =CC=C4) =O) C=C1

• Molecular Formula:

  C30H31FN4O2

• Molecular Weight:

  498.59

• References & Citations:

  [1]Hanumantha Rao Madala, et al. Beyond Brooding on Oncometabolic Havoc in IDH-Mutant Gliomas and AML: Current and Future Therapeutic Strategies. Cancers (Basel) . 2018 Feb 11;10 (2) :49.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• Isoform:

  IDH1

• CAS Number:

  1355324-14-9