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PM226

CAT: 0804-HY-136238Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-136238Size:1 Each
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Description
PM226 is a selective cannabinoid CB2R agonist (Ki (CB2R) =13 nM; EC50 (CB2R) =39 nM; Ki (CB1R) >40 μM; ) with neuroprotective properties in vitro and vivo[1].
CAS Number
1949726-13-9
UNSPSC
12352005
Target
Cannabinoid Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/pm226.html
Solubility
10 mM in DMSO
Smiles
CC1(C)OC2=CC(C(C)(C)CCCCCC)=CC(OC)=C2C3=C1C=NO3
Molecular Formula
C22H31NO3
Molecular Weight
357.49
References & Citations
[1]Gemma Navarro, et al. Targeting Cannabinoid CB2 Receptors in the Central Nervous System. Medicinal Chemistry Approaches with Focus on Neurodegenerative Disorders. Front Neurosci. 2016 Sep 13;10:406.|[2]M Gómez-Cañas, et al. Biological characterization of PM226, a chromenoisoxazole, as a selective CB2 receptor agonist with neuroprotective profile. Pharmacol Res. 2016 Aug;110:205-215.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
CB2

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CatalogName
GTR19190441-01PM226

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