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StRIP16

CAT: 0804-HY-136197Size: 500 µgDry Ice: NoHazardous: No
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CAT#:0804-HY-136197Size:500 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
StRIP16, bioavailable StRIP3 analogue, is a double-stapled peptide which can bind to Rab8a GTPase, with a Kd of 12.7 μM[1].
CAS Number
2761279-63-2
UNSPSC
12352005
Target
Ras
Type
Reference compound
Related Pathways
GPCR/G Protein; MAPK/ERK Pathway
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/strip16.html
Solubility
10 mM in DMSO
Smiles
CC(C)C[C@H](NC([C@H](CC1=CN=CN1)NC([C@H](CC2=CC=C(O)C=C2)NC([C@]3(C)CCC/C=C/CCC[C@](C(N[C@@H](CCC(N)=O)C(N[C@@H](CC4=CNC5=CC=CC=C45)C(N[C@@H](CC6=CC=CC=C6)C(N3)=O)=O)=O)=O)(C)NC([C@H](CCC(O)=O)NC([C@H](CC(N)=O)NC([C@@H](NC(C)=O)CC(O)=O)=O)=O)=O)=O)=O)=O)C(N[C@@]7(C)CCC/C=C/CCC[C@](C(N[C@@H](C(C)C)C(N)=O)=O)(C)NC([C@H](CC(N)=O)NC([C@H](CC8=CC=CC=C8)NC([C@H](CC9=CC=CC=C9)NC7=O)=O)=O)=O)=O
Molecular Formula
C116H154N24O26
Molecular Weight
2300.65
References & Citations
[1]Cromm PM, et, al. Protease-Resistant and Cell-Permeable Double-Stapled Peptides Targeting the Rab8a GTPase. ACS Chem Biol. 2016 Aug 19;11 (8) :2375-82.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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