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SRT3657

CAT: 0804-HY-136094Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-136094Size:1 Each
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Description
SRT3657 is a brain-permeable activator of SIRT1, with neuroprotective effect[1].
CAS Number
1383551-17-4
UNSPSC
12352005
Target
Sirtuin
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Epigenetics
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/srt3657.html
Solubility
10 mM in DMSO
Smiles
O=C(N1CCC(OCC2=CN=C(SC(C3=CC=CC=C3NC(C4=NC(CCCC)=NC(NCCN(C(OC(C)(C)C)=O)C)=C4)=O)=N5)C5=C2)CC1)OC(C)(C)C
Molecular Formula
C40H54N8O6S
Molecular Weight
774.97
References & Citations
[1]Gräff J, et al. A dietary regimen of caloric restriction or pharmacological activation of SIRT1 to delay the onset of neurodegeneration. J Neurosci. 2013 May 22;33 (21) :8951-60.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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CatalogName
GTR19204732-01SRT3657

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