PTAD-PEG4-amine

• Description:

  PTAD-PEG4-amine is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) [1].

• UNSPSC:

  12352203

• Hazard Statement:

  H302-H315-H319-H335

• Target:

  ADC Linker

• Type:

  ADC Related

• Related Pathways:

  Antibody-drug Conjugate/ADC Related

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/ptad-peg4-amine.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C(NNC1=O)N1C2=CC=C(OCCNC(CCOCCOCCOCCOCCN)=O)C(OC)=C2

• Molecular Formula:

  C22H35N5O9

• Molecular Weight:

  513.54

• Precautions:

  P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

• References & Citations:

  [1]Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16 (5) :315-337.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  ADC Related

• Clinical Information:

  No Development Reported

• Isoform:

  Cleavable Linker