Aniline-MPB-amino-C3-PBD

Aniline-MPB-amino-C3-PBD

• CAS Number: 2412923-79-4
• UNSPSC Description: Aniline-MPB-amino-C3-PBD is a cytotoxic agent comprised non-alkylating group. Aniline-MPB-amino-C3-PBD is a sequence-selective DNA minor-groove binding agent. Aniline-MPB-amino-C3-PBD acts as the payload for ADCs. Antimicrobial activity[1].
• Target Antigen: ADC Cytotoxin; Bacterial
• Type: ADC Related
• Related Pathways: Antibody-drug Conjugate/ADC Related;Anti-infection
• Applications: Cancer-programmed cell death
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/aniline-mpb-amino-c3-pbd.html
• Solubility: 10 mM in DMSO
• Smiles: O=C(N(CCCC1)[C@]1([H])CN2)C3=C2C=C(OCCCC(NC4=CN(C)C(C(NC5=CC=C(C6=CN(C)C(C(NC7=CC=C(N)C=C7)=O)=C6)C=C5)=O)=C4)=O)C(OC)=C3
• Molecular Weight: 758.86
• References & Citations: [1]David Edwin Thurston, et al. Polycyclic amides as cytotoxic agents. WO2020049286A1.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported