Holomycin

• Description:

  Holomycin is a secondary metabolite of the dithiolopyrrolone class. Holomycin also is a broad spectrum antibiotic. Holomycin has antitumor activity and can act in vivo on RNA synthesis[1].

• UNSPSC:

  12352005

• Target:

  Antibiotic; DNA/RNA Synthesis

• Type:

  Reference compound

• Related Pathways:

  Anti-infection; Cell Cycle/DNA Damage

• Applications:

  COVID-19-anti-virus

• Field of Research:

  Cancer; Infection

• Assay Protocol:

  https://www.medchemexpress.com/holomycin.html

• Purity:

  95.09

• Solubility:

  10 mM in DMSO

• Smiles:

  CC(NC1=C2C(NC1=O)=CSS2)=O

• Molecular Formula:

  C7H6N2O2S2

• Molecular Weight:

  214.26

• References & Citations:

  [1]Paloma Liras, et al. Holomycin, a dithiolopyrrolone compound produced by Streptomyces clavuligerus. Appl Microbiol Biotechnol. 2014 Feb;98 (3) :1023-30.

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  -20°C (Powder, sealed storage, away from moisture)

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  [488-04-0]