Arzoxifene

CAT: 0804-HY-13556Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-13556Size:1 Each
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Description
Arzoxifene (LY353381) is an orally active selective estrogen receptor modulator with a fixed ring structure similar to raloxifene. Arzoxifene has minimal side effects with powerful antiestrogenic effects on breast cancer and endometrium, with equally strong favorable estrogenic effects on bone and lipid profile[1].
CAS Number
[182133-25-1]
Product Name Alternative
LY353381; SERM III
UNSPSC
12352005
Hazard Statement
H302-H312-H332
Target
Estrogen Receptor/ERR
Type
Reference compound
Related Pathways
Vitamin D Related/Nuclear Receptor
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease; Cancer
Assay Protocol
https://www.medchemexpress.com/arzoxifene.html
Solubility
10 mM in DMSO
Smiles
OC1=CC=C(C(OC2=CC=C(OCCN3CCCCC3)C=C2)=C(C4=CC=C(OC)C=C4)S5)C5=C1
Molecular Formula
C28H29NO4S
Molecular Weight
475.60
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P363-P501
References & Citations
[1]Jackson LR, et al. Arzoxifene: the evidence for its development in the management of breast cancer. Core Evid. 2008;2 (4) :251-258.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Launched

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