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4-Acetylsimvastatin

CAT: 0804-HY-135405-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-135405-01Size:10 mg
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Description
4-Acetylsimvastatin is an acetylated simvastatin. Simvastatin is a competitive inhibitor of HMG-CoA reductase with a Ki of 0.2 nM[1].
CAS Number
145576-25-6
UNSPSC
12352005
Hazard Statement
H361
Target
Others
Type
Reference compound
Related Pathways
Others
Applications
Cancer-programmed cell death
Field of Research
Cardiovascular Disease; Cancer
Assay Protocol
https://www.medchemexpress.com/4-acetylsimvastatin.html
Solubility
10 mM in DMSO
Smiles
CCC(C)(C)C(O[C@H]1C[C@@H](C)C=C2C=C[C@H](C)[C@H](CC[C@@H]3C[C@@H](OC(C)=O)CC(O3)=O)[C@@]12[H])=O
Molecular Formula
C27H40O6
Molecular Weight
460.60
Precautions
P280-P405-P501
References & Citations
[1]Brian Morgan, ey al. Methods for Making Simvastatin and Intermediates. US20110059493A1.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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