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Desfluoro-atorvastatin

CAT: 0804-HY-135373Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-135373Size:1 mg
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Description
Desfluoro-atorvastatin is an impurity of Atorvastatin[1]. Atorvastatin is an orally active 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitor, has the ability to effectively decrease blood lipids[2].
CAS Number
433289-84-0
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
Drug Metabolite
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/desfluoro-atorvastatin.html
Solubility
10 mM in DMSO
Smiles
O=C(C1=C(C(C)C)N(CC[C@@H](O)C[C@@H](O)CC(O)=O)C(C2=CC=CC=C2)=C1C3=CC=CC=C3)NC4=CC=CC=C4
Molecular Formula
C33H36N2O5
Molecular Weight
540.65
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
References & Citations
[1]Ertürk S, et al. An HPLC method for the determination of atorvastatin and its impurities in bulk drug and tablets. J Pharm Biomed Anal. 2003 Dec 4;33 (5) :1017-23.|[2]Santodomingo-Garzón T, et al. Atorvastatin inhibits inflammatory hypernociception. Br J Pharmacol. 2006 Sep;149 (1) :14-22.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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