Biliverdin

• Description :

  Biliverdin, a tetrapyrrolic pigment, is a product of heme catabolism. Heme is broken down into Biliverdin and carbon monoxide and iron by heme oxidase. Biliverdin is then quickly broken down to bilirubin by Biliverdin reductase. Biliverdin can mediate the protective effects of HO-1 in many disease models including IRI and organ transplantation. Biliverdin exhibits anti-mutagenic, an antioxidant, anti-inflammatory, and immunosuppressant properties[1][2][3].

• UNSPSC :

  12352005

• Hazard Statement :

  H315, H319

• Target :

  Endogenous Metabolite

• Type :

  Natural Products

• Related Pathways :

  Metabolic Enzyme/Protease

• Applications :

  Metabolism-protein/nucleotide metabolism

• Field of Research :

  Inflammation/Immunology

• Assay Protocol :

  https://www.medchemexpress.com/biliverdin.html

• Purity :

  99.0

• Solubility :

  DMSO : 3 mg/mL (ultrasonic; warming)

• Smiles :

  OC(CCC(C(C)=C(N1)/C=C2C(C=C)=C(C(N/2)=O)C)=C1/C=C3C(CCC(O)=O)=C(C(/C=C4C(C)=C(C(N/4)=O)C=C)=N/3)C)=O

• Molecular Formula :

  C33H34N4O6

• Molecular Weight :

  582.65

• Precautions :

  H315, H319

• References & Citations :

  [1]McDonnell MC, et al. Biochemistry, Biliverdin. 2023 May 1. In: StatPearls [Internet]. Treasure Island (FL) : StatPearls Publishing; 2025 Jan. |[2]Jansen, T., & Daiber, A. (2012) . Direct Antioxidant Properties of Bilirubin and Biliverdin. Is there a Role for Biliverdin Reductase?. Frontiers in pharmacology, 3, 30.|[3]Ollinger, R., et al., (2007) . Therapeutic applications of bilirubin and biliverdin in transplantation. Antioxidants & redox signaling, 9 (12), 2175–2185.

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  -20°C (Powder, protect from light)

• Scientific Category :

  Natural Products

• Clinical Information :

  No Development Reported

• Isoform :

  Human Endogenous Metabolite

• CAS Number :

  [114-25-0]