DSPE-PEG2-mal

CAT: 0804-HY-134745-01Size: 5 mgDry Ice: NoHazardous: No

1 / 1

CAT#:0804-HY-134745-01Size:5 mg

Selected

24/48H Stock Items & 2 to 6 Weeks non Stock Items.

Quick Request Actions

Description

DSPE-PEG2-mal is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

CAS Number

1915739-87-5

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

PROTAC Linkers

Type

Reference compound

Related Pathways

PROTAC

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/dspe-peg2-mal.html

Purity

99.91

Solubility

10 mM in DMSO

Smiles

CCCCCCCCCCCCCCCCCC(O[C@H](COC(CCCCCCCCCCCCCCCCC)=O)COP(OCCNC(CCOCCOCCNC(CCN1C(C=CC1=O)=O)=O)=O)(O)=O)=O

Molecular Formula

C55H100N3O14P

Molecular Weight

1058.37

Precautions

H302, H315, H319, H335

References & Citations

[1]An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Shipping Conditions

Blue Ice

Storage Conditions

-20°C, 3 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

PEG Linkers

Chemical Information

DSPE-PEG2-mal

CAS Number	1915739-87-5
PubChem CID	156597073
IUPAC Name	[(2R)-3-[2-[3-[2-[2-[3-(2,5-dioxopyrrol-1-yl)propanoylamino]ethoxy]ethoxy]propanoylamino]ethoxy-hydroxyphosphoryl]oxy-2-octadecanoyloxypropyl] octadecanoate
Molecular Formula	C55H100N3O14P
Molecular Weight	1058.4
XLogP	13.1
Topological Polar Surface Area	222
Hydrogen Bond Donor Count	3
Hydrogen Bond Acceptor Count	14
Rotatable Bond Count	56
Heavy Atom Count	73
Formal Charge	0
Complexity	1500

SMILES

CCCCCCCCCCCCCCCCCC(=O)OC[C@H](COP(=O)(O)OCCNC(=O)CCOCCOCCNC(=O)CCN1C(=O)C=CC1=O)OC(=O)CCCCCCCCCCCCCCCCC

InChI

InChI=1S/C55H100N3O14P/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-31-33-54(63)69-47-49(72-55(64)34-32-30-28-26-24-22-20-18-16-14-12-10-8-6-4-2)48-71-73(65,66)70-44-40-57-51(60)38-42-67-45-46-68-43-39-56-50(59)37-41-58-52(61)35-36-53(58)62/h35-36,49H,3-34,37-48H2,1-2H3,(H,56,59)(H,57,60)(H,65,66)/t49-/m1/s1

InChIKey

PFHIBVKYIUDMIC-ANFMRNGASA-N

Chemical Structure

2D Structure

CAS: 1915739-87-5

CID: 156597073

Formula: C55H100N3O14P

MW: 1058.4

Interactive 3D Structure

Loading 3D structure...

View on PubChem Raw 3D data

Computed Properties

Property	Value
Molecular Weight	1058.4
XLogP3	13.1
Hydrogen Bond Donor Count	3
Hydrogen Bond Acceptor Count	14
Rotatable Bond Count	56
Exact Mass	1057.69429187
Monoisotopic Mass	1057.69429187
Topological Polar Surface Area	222 Å²
Heavy Atom Count	73
Formal Charge	0
Complexity	1500
Isotope Atom Count	0
Defined Atom Stereocenter Count	1
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently-Bonded Unit Count	1
Compound Is Canonicalized	Yes

Related Products

Catalog	Name
HY-140956-01	DSPE-PEG8-Mal
HY-140957	Mal-PEG12-DSPE
HY-138395-01	DSPE-PEG6-Mal
HY-W441007-01	DSPE-Mal
HY-133380	DSPE-PEG36-mal
HY-138404	THP-PEG2-Mal
HY-140968-01	Mal-PEG2-alcohol
HY-W010764-01	Biotin-PEG2-Mal
HY-W800648	Mal-PEG2-amide
HY-W352966-01	Mal-PEG2-CH2COOH

Alternative Products

Catalog	Name
MBS5799836	DSPE-PEG2-mal
BA7876-50	DSPE-Mal
GTR19225608-01	DSPE-PEG8-Mal
GTR19225354-01	Mal-PEG12-DSPE
OR1001770	DSPE-PEG6-Mal
OR1025270-01	DSPE-PEG-Mal
T17857-01	DSPE-PEG36-mal
BA2464-250	Mal-PEG2-acid
T87922-01	Mal-PEG2-CH2COOH
T15979	Mal-PEG2-alcohol

DSPE-PEG2-mal

Chemical Information

Related Products

Alternative Products

Popular Products