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Ganfeborole

CAT: 0804-HY-134648Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-134648Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Ganfeborole (GSK656 free base) is a potent, selective and orally active inhibitor of M. tuberculosis leucyl-tRNA synthetase, with an IC50 of 0.20 μM. Ganfeborole can be used for the research of tuberculosis[1].
CAS Number
2131798-12-2
Product Name Alternative
GSK656 (free base) ; GSK3036656 (free base) ; GSK070 (free base)
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
Bacterial
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/ganfeborole.html
Solubility
10 mM in DMSO
Smiles
OB1O[C@H](CN)C2=C(Cl)C=CC(OCCO)=C21
Molecular Formula
C10H13BClNO4
Molecular Weight
257.48
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
References & Citations
[1]Li X, et, al. Discovery of a Potent and Specific M. tuberculosis Leucyl-tRNA Synthetase Inhibitor: (S) -3- (Aminomethyl) -4-chloro-7- (2-hydroxyethoxy) benzo[c][1,2]oxaborol-1 (3H) -ol (GSK656) . J Med Chem. 2017 Oct 12;60 (19) :8011-8026.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 2

Alternative Products

CatalogName
GTR19205699-01Ganfeborole HCl
C04658Ganfeborole hydrochloride

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