2,5-Anhydro-D-glucitol-1,6-diphosphate

2,5-Anhydro-D-glucitol-1,6-diphosphate

• CAS Number: 4429-47-4
• UNSPSC Description: 2,5-Anhydro-D-glucitol-1,6-diphosphate is a limited stimulator of yeast Pyruvate Kinase. 2,5-Anhydro-D-glucitol-1,6-diphosphate is used as an analogue of the a-form, 2,5-anhydro-D-mannitol 1,6-bisphosphate, while is an excellent allosteric activator of Pyruvate Kinase[1].
• Target Antigen: Pyruvate Kinase
• Type: Reference compound
• Related Pathways: Metabolic Enzyme/Protease
• Applications: Metabolism-sugar/lipid metabolism
• Field of Research: Metabolic Disease
• Assay Protocol: https://www.medchemexpress.com/2-5-anhydro-d-glucitol-1-6-diphosphate.html
• Solubility: 10 mM in DMSO
• Smiles: O[C@H]1[C@@H](O)[C@H](OP(O)(O)=O)O[C@@H]1OP(O)(O)=O
• Molecular Weight: 296.06
• References & Citations: [1]Wurster B, et al. Tautomeric and anomeric specificity of allosteric activation of yeast pyruvate kinase by D-fructose 1, 6-bisphosphate and its relevance in D-glucose catabolism. FEBS Lett. 1976 Mar 15;63(1):17-21.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported