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Remogliflozin

CAT: 0804-HY-13414Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-13414Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Remogliflozin is a potent and selective inhibitor of SGLT2 (sodium-glucose cotransporter 2) with Kis of 12.4 and 26 nM for human and rat SGLT2, respectively. Remogliflozin is the active form of Remogliflozin etabonate.
CAS Number
329045-45-6
Product Name Alternative
Remogliflozin A
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
SGLT
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/remogliflozin.html
Solubility
10 mM in DMSO
Smiles
O[C@H]([C@H]([C@@H]([C@@H](CO)O1)O)O)[C@@H]1OC2=NN(C(C)C)C(C)=C2CC3=CC=C(OC(C)C)C=C3
Molecular Formula
C23H34N2O7
Molecular Weight
450.53
Precautions
H302, H315, H319, H335
References & Citations
[1]Fujimori Y, et al. Remogliflozin etabonate, in a novel category of selective low-affinity sodium glucose cotransporter (SGLT2) inhibitors, exhibits antidiabetic efficacy in rodent models. J Pharmacol Exp Ther. 2008 Oct;327 (1) :268-76.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Phase 2
Isoform
SGLT2