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IQZ23

CAT: 0804-HY-133556Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-133556Size:1 Each
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Description
IQZ23 inhibits adipocyte differentiation via AMPK pathway activation. IQZ23 exerts a high efficacy in decreasing the triglyceride level (EC50=0.033 μM) in 3T3-L1 adipocytes. IQZ23 could be used for the research of obesity and related metabolic disorders[1].
CAS Number
2415643-79-5
UNSPSC
12352005
Target
AMPK
Type
Reference compound
Related Pathways
Epigenetics; PI3K/Akt/mTOR
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/iqz23.html
Solubility
10 mM in DMSO
Smiles
COC1=CC=C(NC(C2=NC(C=CC=C3)=C3C(NCCCCN4CCCC4)=N2)=C5C=O)C5=C1
Molecular Formula
C26H29N5O2
Molecular Weight
443.54
References & Citations
[1]Yong Rao, et al. Discovery of a Promising Agent IQZ23 for the Treatment of Obesity and Related Metabolic Disorders. Eur J Med Chem. 2020 Apr 15;192:112172.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
AMPK

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