4-Succinimidyl-oxycarbonyl-α-(2-pyridyldithio)toluene

4-Succinimidyl-oxycarbonyl-α-(2-pyridyldithio)toluene

• CAS Number: 160854-54-6
• UNSPSC Description: 4-Succinimidyl-oxycarbonyl-α-(2-pyridyldithio)toluene is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].
• Target Antigen: ADC Linker
• Type: ADC Related
• Related Pathways: Antibody-drug Conjugate/ADC Related
• Applications: Cancer-programmed cell death
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/4-succinimidyl-oxycarbonyl-α-2-pyridyldithio-toluene.html
• Solubility: 10 mM in DMSO
• Smiles: O=C(ON1C(CCC1=O)=O)C2=CC=C(CSSC3=NC=CC=C3)C=C2
• Molecular Weight: 374.43
• References & Citations: [1]Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported