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O-2050

CAT: 0804-HY-133533Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-133533Size:1 Each
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Description
O-2050 is a high affinity cannabinoid CB1 receptor antagonist with a Ki of 2.5 nM. O-2050 inhibits cannabinoid CB2 receptor (Ki=0.2 nM) . O-2050 can cause locomotor stimulation in mice[1].
CAS Number
1883545-42-3
UNSPSC
12352005
Target
Cannabinoid Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/o-2050.html
Solubility
10 mM in DMSO
Smiles
CS(=O)(NCCCC#CCC1=CC(O)=C([C@@]2([H])[C@](CC=C(C)C2)([H])C(C)(C)O3)C3=C1)=O
Molecular Formula
C23H31NO4S
Molecular Weight
417.56
References & Citations
[1]Jenny L Wiley, et al. Structural and pharmacological analysis of O-2050, a putative neutral cannabinoid CB (1) receptor antagonist. Eur J Pharmacol. 2011 Jan 25;651 (1-3) :96-105.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
CB1; CB2

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