O-2050

• Description :

  O-2050 is a high affinity cannabinoid CB1 receptor antagonist with a Ki of 2.5 nM. O-2050 inhibits cannabinoid CB2 receptor (Ki=0.2 nM) . O-2050 can cause locomotor stimulation in mice[1].

• UNSPSC :

  12352005

• Target :

  Cannabinoid Receptor

• Type :

  Reference compound

• Related Pathways :

  GPCR/G Protein; Neuronal Signaling

• Applications :

  Neuroscience-Neuromodulation

• Field of Research :

  Neurological Disease

• Assay Protocol :

  https://www.medchemexpress.com/o-2050.html

• Solubility :

  10 mM in DMSO

• Smiles :

  CS(=O)(NCCCC#CCC1=CC(O)=C([C@@]2([H])[C@](CC=C(C)C2)([H])C(C)(C)O3)C3=C1)=O

• Molecular Formula :

  C23H31NO4S

• Molecular Weight :

  417.56

• References & Citations :

  [1]Jenny L Wiley, et al. Structural and pharmacological analysis of O-2050, a putative neutral cannabinoid CB (1) receptor antagonist. Eur J Pharmacol. 2011 Jan 25;651 (1-3) :96-105.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• Isoform :

  CB1; CB2

• CAS Number :

  [1883545-42-3]