Mal-PEG36-NHS ester

• Description :

  Mal-PEG36-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

• UNSPSC :

  12352005

• Hazard Statement :

  H302, H315, H319, H335

• Target :

  PROTAC Linkers

• Type :

  Reference compound

• Related Pathways :

  PROTAC

• Applications :

  Cancer-programmed cell death

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/mal-peg36-nhs-ester.html

• Purity :

  95.0

• Solubility :

  DMSO : 62.5 mg/mL (ultrasonic)

• Smiles :

  O=C(C=C1)N(CCC(NCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCC(ON2C(CCC2=O)=O)=O)=O)C1=O

• Molecular Formula :

  C86H159N3O43

• Molecular Weight :

  1923.18

• Precautions :

  H302, H315, H319, H335

• References & Citations :

  [1]"An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562. "

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  -20°C, 3 years (Powder)

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• Isoform :

  Alkyl/ether Linkers; PEG Linkers