Products for Research Use Only
RegisterLogin

Pradimicin A

CAT: 0804-HY-132191Size: 1 EachDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-132191Size:1 Each
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Pradimicin A (PRM-A) is a potent antifungal agent, with an MIC of 4 μg/mL against Candida rugosa. Pradimicin A has antiviral activities against CoV, HIV and other enveloped viruses. Pradimicin A shows aggregation property, and can recognize d-Man in the presence of Ca2+ ion[1][2].
CAS Number
117704-65-1
UNSPSC
12352005
Target
Fungal; HIV; SARS-CoV
Type
Natural Products
Related Pathways
Anti-infection
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/pradimicin-a.html
Solubility
10 mM in DMSO
Smiles
OC1=C2C3=C(O)C(C(N[C@H](C)C(O)=O)=O)=C(C)C=C3[C@@H]([C@H](C2=CC4=C1C(C5=CC(OC)=CC(O)=C5C4=O)=O)O)O[C@H]6[C@@H]([C@H]([C@H]([C@H](O6)C)NC)O[C@H]7[C@@H]([C@H]([C@@H](CO7)O)O)O)O
Molecular Formula
C40H44N2O18
Molecular Weight
840.78
References & Citations
[1]Miyanishi W, et al. d-Mannose binding, aggregation property, and antifungal activity of amide derivatives of pradimicin A. Bioorg Med Chem. 2021 Dec 27;55:116590.|[2]Nakagawa Y, Doi T, Masuda Y, Takegoshi K, Igarashi Y, Ito Y. Mapping of the primary mannose binding site of pradimicin A. J Am Chem Soc. 2011 Nov 2;133 (43) :17485-93.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported

Alternative Products

CatalogName
GTR19221946-01Pradimicin A
TN10083-01Pradimicin T2
GTR19240752-01Pradimicin D
GTR19249201-01Pradimicin L
TN10597-01Pradimicin Q
TN10677-01Pradimicin B
TN10436-01Pradimicin Tl
T32540-01L-Alanyl pradimicin A

Popular Products