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Biperiden (lactate)

CAT: 0804-HY-13204BSize: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-13204BSize:1 Each
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Description
Biperiden (KL 373) lactate is an orally active non-selective muscarinic receptor antagonist that competitively binds to M1 muscarinic receptors. Biperiden (KL 373) lactate inhibits acetylcholine and enhances dopamine signaling in the central nervous system. Biperiden (KL 373) lactate has the potential for the research of Parkinson's disease and other related psychiatric disorders[1][2].
CAS Number
7085-45-2
Product Name Alternative
KL 373 (lactate)
UNSPSC
12352005
Hazard Statement
H302-H312-H332
Target
MAChR
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/biperiden-lactate.html
Solubility
10 mM in DMSO
Smiles
OC(C1C2CC(C=C2)C1)(C3=CC=CC=C3)CCN4CCCCC4.OC(C(O)C)=O
Molecular Formula
C24H35NO4
Molecular Weight
401.54
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P363-P501
References & Citations
[1]Leonie Konczalla, et al. Biperiden and mepazine effectively inhibit MALT1 activity and tumor growth in pancreatic cancer. Int J Cancer. 2020 Mar 15;146 (6) :1618-1630.|[2]Simone Bittencourt, et al. Modification of the natural progression of epileptogenesis by means of biperiden in the pilocarpine model of epilepsy. Epilepsy Res. 2017 Dec;138:88-97. doi: 10.1016/j.eplepsyres.2017.10.019. Epub 2017 Oct 29.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Launched
Isoform
MAChR1

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