MC-Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH (GMP)

CAT:

804-HY-131990G

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CAS Number: 1599440-25-1
UNSPSC Description: MC-Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH GMP is a GMP grade MC-Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH (HY-131990). MC-Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].
Target Antigen: ADC Linker
Type: GMP Small Molecules
Related Pathways: Antibody-drug Conjugate/ADC Related
Applications: Cancer-programmed cell death
Field of Research: Cancer
Assay Protocol: https://www.medchemexpress.com/mc-gly-gly-phe-gly-nh-ch2-o-ch2cooh-gmp.html
Solubility: 10 mM in DMSO
Smiles: OC(COCNC(CNC([C@@H](NC(CNC(CNC(CCCCCN1C(C=CC1=O)=O)=O)=O)=O)CC2=CC=CC=C2)=O)=O)=O
Molecular Weight: 616.62
References & Citations: [1]Masuda, Takeshi, et al. Conjugué anticorps-médicament. WO2014057687A1.
Shipping Conditions: Room temperature
Clinical Information: No Development Reported

Cat	Name
HY-131990G	MC-Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH (GMP)
HY-131990-04	MC-Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH
HY-131990-02	MC-Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH
HY-131990-03	MC-Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH
HY-131990-01	MC-Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH
HY-45672G	Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH (GMP)
HY-131990S	MC-Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH-d5
HY-131990A-02	MC-Gly-Gly-{D-Phe}-Gly-NH-CH2-O-CH2COOH
HY-131990A-01	MC-Gly-Gly-{D-Phe}-Gly-NH-CH2-O-CH2COOH
HY-160453	MC-Gly-Gly-Phe-Gly-NH-CH2-O-cyclopropane-CH2COOH

Cat	Name
T39064-50mg	MC-Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH
T39064-10mg	MC-Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH
T39064-5mg	MC-Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH
T39064-1mg	MC-Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH
T39064-1g	MC-Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH
MBS5799612	MC-Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH
BA2394-1000	Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH
BA2394-250	Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH
MBS5819567	Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH
BA2391-10000	Fmoc-Gly-NH-CH2-O-CH2COOH