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Digoxigenin bisdigitoxoside

CAT: 0804-HY-131486Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-131486Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Digoxigenin bisdigitoxoside is an anticancer agent and an active derivative of cardiac glycosides. Cardiac glycosides exert their apoptotic effects through the Nur77-dependent apoptotic pathway. Digoxigenin bisdigitoxoside is cytotoxic[1].
CAS Number
5297-05-2
UNSPSC
12352005
Hazard Statement
H300
Target
Nuclear Hormone Receptor 4A/NR4A
Type
Reference compound
Related Pathways
Vitamin D Related/Nuclear Receptor
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/digoxigenin-bisdigitoxoside.html
Solubility
10 mM in DMSO
Smiles
O[C@@]12[C@@]([C@](C3=CC(OC3)=O)([H])CC1)([C@@H](C[C@@]4([H])[C@@]2([H])CC[C@@]5([H])[C@@]4(CC[C@@H](C5)O[C@H]6C[C@@H]([C@@H]([C@H](O6)C)O[C@H]7C[C@@H]([C@@H]([C@H](O7)C)O)O)O)C)O)C
Molecular Formula
C35H54O11
Molecular Weight
650.80
Precautions
H300
References & Citations
[1]Li XS, et al. Synthesis of C3-Neoglycosides of digoxigenin and their anticancer activities. Eur J Med Chem. 2018 Feb 10;145:252-262.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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