Chk1-IN-5

Chk1-IN-5

• CAS Number: 2120398-39-0
• UNSPSC Description: Chk1-IN-5 is a potent checkpoint kinase 1 (Chk1) inhibitor. Chk1-IN-5 inhibits Chk1 phosphorylation and inhibits tumor growth in colon cancer xenograft model[1].
• Target Antigen: Checkpoint Kinase (Chk)
• Type: Reference compound
• Related Pathways: Cell Cycle/DNA Damage
• Applications: Cancer-Kinase/protease
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/chk1-in-5.html
• Solubility: 10 mM in DMSO
• Smiles: N#CC1=NC=C(NC2=NNC(C3=C(OC)C=C(F)C=C3OCCCN)=C2)N=C1
• Molecular Weight: 383.38
• References & Citations: [1]Xiong Cai, et al. 3,5-disubstituted pyrazoles useful as checkpoint kinase 1 (chk1) inhibitors, and their preparations and applications. WO2017132928A1.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported