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Cis-ACCP

CAT: 0804-HY-131417Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-131417Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Cis-ACCP is an orally active antimetastatic matrix metalloproteinase-2 (MMP-2) selective inhibitor. cis-ACCP can inhibit MMP-2 and MMP-9 with IC50 values of 4 μM and 20 μM, respectively. cis-ACCP can be used for the research of a variety of chronic diseases[1].
CAS Number
777075-44-2
UNSPSC
12352211
Target
MMP
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Cancer; Infection; Inflammation/Immunology; Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/cis-accp.html
Purity
97.0
Solubility
H2O : 25 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
OP(O)(C(N[C@H]1[C@@H](N)CCCC1)=O)=O
Molecular Formula
C7H15N2O4P
Molecular Weight
222.18
References & Citations
[1]Hoffman, Amnon et al. Carbamoylphosphonate matrix metalloproteinase inhibitors 6: cis-2-aminocyclohexylcarbamoylphosphonic acid, a novel orally active antimetastatic matrix metalloproteinase-2 selective inhibitor--synthesis and pharmacodynamic and pharmacokinetic analysis. Journal of medicinal chemistry vol. 51,5 (2008) : 1406-14.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
MMP-2; MMP-9

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