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Cadein1

CAT: 0804-HY-131143Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-131143Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Cadein1, an isoquinolinium derivative, leads to a G2/M delay and caspase-dependent apoptosis in cancer cells with non- functional p53[1].
UNSPSC
12352005
Target
Apoptosis
Type
Reference compound
Related Pathways
Apoptosis
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/cadein1.html
Solubility
10 mM in DMSO
Smiles
COC1=C(C=C2C(CCCCCCCCCCCCCCC)=[N+](CCC2=C1)CC3=C(C=CC=C3F)F)OC.[I-]
Molecular Formula
C33H48F2INO2
Molecular Weight
655.64
References & Citations
[1]Eun Ryoung Jang, et al. A new isoquinolinium derivative, Cadein1, preferentially induces apoptosis in p53-defective cancer cells with functional mismatch repair via a p38-dependent pathway. J Biol Chem. 2010 Jan 29;285 (5) :2986-95.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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