Mytoxin B

• Description :

  Mytoxin B is an ADC cytotoxin. Mytoxin B is a satratoxin-type trichothecene macrolide and is similar to the effect of LY294002 (HY-10108) . Mytoxin B induces cell apoptosis via PI3K/Akt pathway[1].

• UNSPSC :

  12352005

• Target :

  ADC Payload; Apoptosis; PI3K

• Type :

  Natural Products

• Related Pathways :

  Antibody-drug Conjugate/ADC Related; Apoptosis; PI3K/Akt/mTOR

• Applications :

  Cancer-Kinase/protease

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/mytoxin-b.html

• Solubility :

  10 mM in DMSO

• Smiles :

  CC1=C[C@](O[C@H]2[C@]3(OC3)[C@]4(C)[C@@H](C2)OC(/C=C/CC[C@@]5(C(C)=O)OCC/C([C@H]5O)=C/C(OC6)=O)=O)([H])[C@]46CC1

• Molecular Formula :

  C29H36O9

• Molecular Weight :

  528.59

• References & Citations :

  [1]Huiliang Song, et al. Mytoxin B and Myrothecine A Induce Apoptosis in Human Hepatocarcinoma Cell Line SMMC-7721 via PI3K/Akt Signaling Pathway. Molecules. 2019 Jun 20;24 (12) :2291.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Natural Products

• Clinical Information :

  No Development Reported

• CAS Number :

  [105049-15-8]