2,3-Dehydro-3,4-dihydro ivermectin

2,3-Dehydro-3,4-dihydro ivermectin

• CAS Number: 1135339-49-9
• UNSPSC Description: 2,3-Dehydro-3,4-dihydro ivermectin is an analog of ivermectin (HY-15310) and an anthelmintic. 2,3-Dehydro-3,4-dihydro ivermectin has activity against L. amazonensis promastigotes and amastigotes (IC50s=13.8 and 3.6 µM, respectively) without inducing cytotoxicity to macrophages (IC50= 65.5 µM).
• Target Antigen: Parasite
• Type: Reference compound
• Related Pathways: Anti-infection
• Applications: COVID-19-immunoregulation
• Field of Research: Infection
• Assay Protocol: https://www.medchemexpress.com/2-3-dehydro-3-4-dihydro-ivermectin.html
• Solubility: 10 mM in DMSO
• Smiles: O[C@]1(C(C(O[C@]2([H])C[C@](O[C@]3([H])[C@@H](C)CC)(CC[C@@H]3C)O[C@@](C/C=C4\C)([H])C2)=O)=C[C@@H]5C)[C@]([C@@H]5O)([H])OC/C1=C\C=C\[C@@H]([C@@H]4O[C@H](O[C@H]6C)C[C@@H]([C@H]6O[C@H](O[C@H]7C)C[C@@H]([C@H]7O)OC)OC)C
• Molecular Weight: 875.09
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported