2,3-Dehydro-3,4-dihydro ivermectin

• UNSPSC Description:

  2,3-Dehydro-3,4-dihydro ivermectin is an analog of ivermectin (HY-15310) and an anthelmintic. 2,3-Dehydro-3,4-dihydro ivermectin has activity against L. amazonensis promastigotes and amastigotes (IC50s=13.8 and 3.6 µM, respectively) without inducing cytotoxicity to macrophages (IC50= 65.5 µM).

• Target Antigen:

  Parasite

• Type:

  Reference compound

• Related Pathways:

  Anti-infection

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Infection

• Assay Protocol:

  https://www.medchemexpress.com/2-3-dehydro-3-4-dihydro-ivermectin.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O[C@]1(C(C(O[C@]2([H])C[C@](O[C@]3([H])[C@@H](C)CC)(CC[C@@H]3C)O[C@@](C/C=C4\C)([H])C2)=O)=C[C@@H]5C)[C@]([C@@H]5O)([H])OC/C1=C\C=C\[C@@H]([C@@H]4O[C@H](O[C@H]6C)C[C@@H]([C@H]6O[C@H](O[C@H]7C)C[C@@H]([C@H]7O)OC)OC)C

• Molecular Weight:

  875.09

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  1135339-49-9