Febuxostat acyl glucuronide

• UNSPSC Description:

  Febuxostat acyl glucuronide (Febuxostat acyl-β-D-glucuronide) is a metabolite of Febuxostat (HY-14268). Febuxostat is a potent, selective and non-purine xanthine oxidase (XO) inhibitor[1].

• Target Antigen:

  Drug Metabolite; Xanthine Oxidase

• Type:

  Reference compound

• Related Pathways:

  Metabolic Enzyme/Protease

• Applications:

  Metabolism-protein/nucleotide metabolism

• Field of Research:

  Metabolic Disease

• Assay Protocol:

  https://www.medchemexpress.com/febuxostat-acyl-glucuronide.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O[C@H]1[C@H](OC(C2=C(C)N=C(C3=CC=C(OCC(C)C)C(C#N)=C3)S2)=O)O[C@H](C(O)=O)[C@@H](O)[C@@H]1O

• Molecular Weight:

  492.50

• References & Citations:

  [1]Bishoy Kamel, et al. Clinical Pharmacokinetics and Pharmacodynamics of Febuxostat. Clin Pharmacokinet. 2017 May;56(5):459-475.|[2]Kamel B, et al. Clinical Pharmacokinetics and Pharmacodynamics of Febuxostat. Clin Pharmacokinet. 2017 May;56(5):459-475.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  1351692-92-6