Febuxostat acyl glucuronide

Febuxostat acyl glucuronide

• CAS Number: 1351692-92-6
• UNSPSC Description: Febuxostat acyl glucuronide (Febuxostat acyl-β-D-glucuronide) is a metabolite of Febuxostat (HY-14268). Febuxostat is a potent, selective and non-purine xanthine oxidase (XO) inhibitor[1].
• Target Antigen: Drug Metabolite; Xanthine Oxidase
• Type: Reference compound
• Related Pathways: Metabolic Enzyme/Protease
• Applications: Metabolism-protein/nucleotide metabolism
• Field of Research: Metabolic Disease
• Assay Protocol: https://www.medchemexpress.com/febuxostat-acyl-glucuronide.html
• Solubility: 10 mM in DMSO
• Smiles: O[C@H]1[C@H](OC(C2=C(C)N=C(C3=CC=C(OCC(C)C)C(C#N)=C3)S2)=O)O[C@H](C(O)=O)[C@@H](O)[C@@H]1O
• Molecular Weight: 492.50
• References & Citations: [1]Bishoy Kamel, et al. Clinical Pharmacokinetics and Pharmacodynamics of Febuxostat. Clin Pharmacokinet. 2017 May;56(5):459-475.|[2]Kamel B, et al. Clinical Pharmacokinetics and Pharmacodynamics of Febuxostat. Clin Pharmacokinet. 2017 May;56(5):459-475.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported