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Phthalimide-PEG3-C2-OTs

CAT: 0804-HY-129772-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-129772-01Size:25 mg
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Description
Phthalimide-PEG3-C2-OTs (Compound 5) is a PROTAC linker, which refers to the PEGs composition. Phthalimide-PEG3-C2-OTs can be used in the synthesis of a series of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
CAS Number
382162-12-1
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
PROTAC Linkers
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/phthalimide-peg3-c2-ots.html
Solubility
10 mM in DMSO
Smiles
CC(C=C1)=CC=C1S(=O)(OCCOCCOCCOCCN2C(C3=C(C=CC=C3)C2=O)=O)=O
Molecular Formula
C23H27NO8S
Molecular Weight
477.53
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
References & Citations
[1]Stegmaier P, et al. Photoactive branched and linear surface architectures for functional and patterned immobilization of proteins and cells onto surfaces: a comparative study. Chemphyschem. 2009 Feb 2;10 (2) :357-69.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
PEG Linkers

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