Products for Research Use Only
RegisterLogin

Pulrodemstat

CAT: 0804-HY-129388ASize: 1 EachDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-129388ASize:1 Each
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Pulrodemstat (CC-90011) is a potent, selective, reversible and orally active inhibitor of lysine specific demethylase-1 (LSD1) with an IC50 of 0.25 nM. Pulrodemstat is less enzymatic inhibition against LSD2, MOA-A, and MAO-B. Pulrodemstat induces acute myeloid leukemia (AML) and small cell lung cancer (SCLC) cells differentiation and has potent anticancer activity[1].
CAS Number
1821307-10-1
Product Name Alternative
CC-90011; LSD1-IN-7
UNSPSC
12352005
Target
Histone Demethylase
Type
Reference compound
Related Pathways
Epigenetics
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/pulrodemstat.html
Solubility
10 mM in DMSO
Smiles
N#CC1=CC=C(C(N=C(N2CCC(N)CC2)N3C)=C(C4=CC=C(OC)C(F)=C4)C3=O)C=C1F
Molecular Formula
C24H23F2N5O2
Molecular Weight
451.47
References & Citations
[1]Toufike Kanouni, et al. Discovery of CC-90011: A Potent and Selective Reversible Inhibitor of Lysine Specific Demethylase 1 (LSD1) . J Med Chem. 2020 Dec 10;63 (23) :14522-14529.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 2
Isoform
KDM1/LSD1

Alternative Products

CatalogName
T39258-01Pulrodemstat
T39258L-01Pulrodemstat HCl
GTR19177139-01Pulrodemstat benzenesulfonate
T11883-01Pulrodemstat Methylbenzenesulfonate
A24339-10Pulrodemstat benzenesulfonate 10mg
A24339-5Pulrodemstat benzenesulfonate 5mg
A24339-100Pulrodemstat benzenesulfonate 100mg
A24339-50Pulrodemstat benzenesulfonate 50mg
S0356-25mgPulrodemstat (CC-90011) besylate

Popular Products