Products for Research Use Only

TAB29

CAT: 0804-HY-128592Size: 1 EachDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-128592Size:1 Each
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
TAB29 is a potent inhibitor of peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (Pin1) with an IC50 of 874 nM, possesses therapeutic potential for human cancers[1].
CAS Number
2361144-71-8
UNSPSC
12352005
Target
PIN1
Type
Reference compound
Related Pathways
PI3K/Akt/mTOR
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/tab29.html
Solubility
10 mM in DMSO
Smiles
C1(OCC2=CC=CC=C2)=CC(OCC3=CC=CC=C3)=C4C(OC=C4C5=CC=CC=C5)=C1
Molecular Formula
C28H22O3
Molecular Weight
406.47
References & Citations
[1]Fan X, et al. Discovery of 4,6-bis (benzyloxy) -3-phenylbenzofuran as a novel Pin1 inhibitor to suppress hepatocellular carcinoma via upregulating microRNA biogenesis. Bioorg Med Chem. 2019 Jun 1;27 (11) :2235-2244.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported