Cephradine (monohydrate)

CAT: 0804-HY-128449-01Size: 100 mgDry Ice: NoHazardous: No
CAT#:0804-HY-128449-01Size:100 mg
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Description
Cephradine (Cefradine) monohydrate is a broad-spectrum and orally active cephalosporin. Cephradine monohydrate is active against both grampositive and gram-negative pathogens and effective in eradicating most penicillinase-producing organisms known to be resistant to penicillin G, penicillin V, and ampicillin. Cephradine monohydrate has been used in the research of genitourinary, gastrointestinal and respiratory tract infections, and in infections of the skin and soft tissues. Cephradine monohydrate blocks solar-ultraviolet induced skin inflammation through direct inhibition of TOPK[1][2][3].
CAS Number
[75975-70-1]
Product Name Alternative
Cefradine (monohydrate)
UNSPSC
12352005
Target
Antibiotic; Bacterial; TOPK
Type
Reference compound
Related Pathways
Anti-infection; Cell Cycle/DNA Damage
Applications
COVID-19-immunoregulation
Field of Research
Infection; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/cephradine-monohydrate.html
Purity
91.02
Solubility
10 mM in DMSO
Smiles
O=C(C(N12)=C(C)CS[C@]2([H])[C@H](NC([C@H](N)C3=CCC=CC3)=O)C1=O)O.[H]O[H]
Molecular Formula
C16H21N3O5S
Molecular Weight
367.42
References & Citations
[1]Schwinghammer TL, et al. Pharmacokinetics of cephradine administered intravenously and orally to young and elderly subjects. J Clin Pharmacol. 1990;30 (10) :893-899|[2]Caloza DL Jr, et al. Intravenous use of cephradine and cefazolin against serious infections. Antimicrob Agents Chemother. 1979;15 (1) :119-122.|[3]Kang S, et al. In Vitro and In Vivo Antimicrobial Activity of Antibiotic-Conjugated Carriers with Rapid pH-Responsive Release Kinetics. Adv Healthc Mater. 2019;8 (14) :e1900247.|[4]Fan X, et al. Cefradine blocks solar-ultraviolet induced skin inflammation through direct inhibition of T-LAK cell-originated protein kinase. Oncotarget. 2016;7 (17) :24633-24645.
Shipping Conditions
Room Temperature
Storage Conditions
Store at room temperature, keep dry and cool
Scientific Category
Reference compound1
Clinical Information
Launched
Isoform
β-lactam

Related Products

CatalogName
HY-B1156-01Cephradine
HY-B1156RCephradine (Standard)
HY-B1156ACephradine (sodium)
HY-145586AOnradivir (monohydrate)
HY-D0858AMES (monohydrate)
HY-13226AGalunisertib (monohydrate)
HY-N1131BTriacetonamine (monohydrate)
HY-B1369-01Imipenem (monohydrate)
HY-13756A-01Tacrolimus (monohydrate)
HY-10001A-01Calcipotriol (monohydrate)

Alternative Products

CatalogName
MBS5768883Cephradine monohydrate
A17949-5Cephradine monohydrate 5mg
A17949-1Cephradine monohydrate 1mg
A17949-10Cephradine monohydrate 10mg
A17949-25Cephradine monohydrate 25mg
MBS3604337-01Cephradine
BIC0102-01Cephradine hydrate
MF-0144083-01Cephradine dihydrate
MF-0143791-01Cephradine sodium
TRC-C261802-25MGCephradine-d5

Popular Products