4'-Deoxyphlorizin

• Description:

  4'-Deoxyphlorizin is an inhibitor of the glucose transport system. 4'-Deoxyphlorizi has good phlorizin hydrolase inhibitory activity with the Km value of 0.59 nM and the Ki value of 0.33 nM, respectively[1].

• UNSPSC:

  12352005

• Target:

  GLUT

• Type:

  Reference compound

• Related Pathways:

  Membrane Transporter/Ion Channel

• Applications:

  Metabolism-sugar/lipid metabolism

• Field of Research:

  Metabolic Disease

• Assay Protocol:

  https://www.medchemexpress.com/4-deoxyphlorizin.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C(C1=C(O)C=CC=C1O[C@H]2[C@@H]([C@H]([C@@H]([C@@H](CO)O2)O)O)O)CCC3=CC=C(O)C=C3

• Molecular Formula:

  C21H24O9

• Molecular Weight:

  420.41

• References & Citations:

  [1]J O Evans, et al. The affinity of phlorizin-like compounds for a beta-glucosidase in intestinal brush borders: comparison with the glucose transport system. Arch Biochem Biophys. 1980 Feb;199 (2) :342-8.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  4319-68-0