Cinitapride (monotartrate)

• Description:

  Cinitapride monotartrate is a 5-HT1A and 5-HT4 agonist. Cinitapride monotartrate is also a 5-HT2A and D2 antagonist. Cinitapride monotartrate can be used for the research of functional dyspepsia[1][2].

• UNSPSC:

  12352005

• Target:

  5-HT Receptor; Dopamine Receptor

• Type:

  Reference compound

• Related Pathways:

  GPCR/G Protein; Neuronal Signaling

• Applications:

  Neuroscience-Neuromodulation

• Field of Research:

  Neurological Disease

• Assay Protocol:

  https://www.medchemexpress.com/cinitapride-monotartrate.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C (NC1CCN (CC2CC=CCC2) CC1) C3=CC ([N+] ([O-]) =O) =C (N) C=C3OCC.O=C (O) [C@H] (O) [C@@H] (O) C (O) =O

• Molecular Formula:

  C25H36N4O10

• Molecular Weight:

  552.57

• References & Citations:

  [1]Du Y, et al. Efficacy and safety of cinitapride in the treatment of mild to moderate postprandial distress syndrome-predominant functional dyspepsia. J Clin Gastroenterol. 2014 Apr;48 (4) :328-35.|[2]Alarcón de la Lastra C, et al. Effects of cinitapride on gastric ulceration and secretion in rats. Inflamm Res. 1998 Mar;47 (3) :131-6. |[3]Parthena MARTIN, et al. Compositions and methods for treating seizure disorders. Patent WO2018060732A2.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  Launched

• Isoform:

  5-HT1 Receptor;5-HT2 Receptor; Apolipoprotein D; D2 Receptor; mLAG-3; α-1 microglobulin

• CAS Number:

  1207859-16-2