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Apraclonidine

CAT: 0804-HY-12720Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-12720Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Apraclonidine (ALO 2145 (free base) ), a selective α2 and weak α1 receptor agonist activity, effectively low intraocular pressure (IOP) in human eyes. Apraclonidine hydrochloride is a topical ophthalmic solution[1][2].
CAS Number
66711-21-5
Product Name Alternative
ALO 2145 (free base)
UNSPSC
12352005
Hazard Statement
H315-H319-H320
Target
Adrenergic Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
COVID-19-immunoregulation
Field of Research
Infection; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/apraclonidine.html
Solubility
10 mM in DMSO
Smiles
NC1=CC(Cl)=C(NC2=NCCN2)C(Cl)=C1
Molecular Formula
C9H10Cl2N4
Molecular Weight
245.11
Precautions
P264-P280-P302+P352-P305+P351+P338-P362
References & Citations
[1]Subhashie Wijemanne, et al. Apraclonidine in the treatment of ptosis. J Neurol Sci|[2]R V Searles, et al. Aqueous humor dynamics in anesthetized rats infused with intracameral apraclonidine. Pharmacology. 1999 Apr;58 (4) :220-6.|[3]Yoriko Hayasaka, et al. Effects of topical antiglaucoma eye drops on prostaglandin E (2) -induced aqueous flare elevation in pigmented rabbits. Invest Ophthalmol Vis Sci
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Launched
Isoform
α adrenergic receptor

Alternative Products

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GTR19188130-01Apraclonidine
002807-01Apraclonidine Hydrochloride
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S6583-01Apraclonidine HCl
CS-O-58977N-Nitroso Apraclonidine Impurity 1
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