Chrysomycin A

• Description :

  Chrysomycin A (Chr-A), an antibiotic, can be obtained from Streptomyces. Chrysomycin A exhibits antitumor and anti-tuberculous and MRSA activities. As for glioblastoma, Chrysomycin A inhibits the proliferation, migration, and invasion of cancer cells through the Akt/GSK-3β/β-catenin signaling pathway[1].

• Product Name Alternative :

  Chr-A

• UNSPSC :

  12352005

• Hazard Statement :

  H302+H312-H319-H351

• Target :

  Akt; Antibiotic; Bacterial; c-Myc; GSK-3; β-catenin

• Type :

  Reference compound

• Related Pathways :

  Anti-infection; Apoptosis; PI3K/Akt/mTOR; Stem Cell/Wnt

• Applications :

  COVID-19-immunoregulation

• Field of Research :

  Cancer; Infection

• Assay Protocol :

  https://www.medchemexpress.com/chrysomycin-a.html

• Purity :

  98.0

• Solubility :

  10 mM in DMSO

• Smiles :

  O=C1C2=CC(C=C)=CC(OC)=C2C3=CC(OC)=C4C(O)=CC=C([C@H]5[C@@H]([C@]([C@H]([C@@H](C)O5)O)(C)O)O)C4=C3O1

• Molecular Formula :

  C28H28O9

• Molecular Weight :

  508.52

• Precautions :

  P264-P270-P280-P302+P352-P305+P351+P338-P330-P362+P364-P405-P501

• References & Citations :

  [1]Liu DN, et al. Chrysomycin A Inhibits the Proliferation, Migration and Invasion of U251 and U87-MG Glioblastoma Cells to Exert Its Anti-Cancer Effects. Molecules. 2022 Sep 20;27 (19) :6148.

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  -20°C (Powder, protect from light, stored under nitrogen)

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [82196-88-1]