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Denopterin

CAT: 0804-HY-121207Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-121207Size:1 Each
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Description
Denopterin is a dihydrofolate reductase (DHFR) inhibitor and an antifolate agent. Denopterin is an antimetabolite that has toxic effects on cells and can be used for cancer[1].
CAS Number
22006-84-4
Product Name Alternative
Pteroylglutamic acid
UNSPSC
12352005
Target
Antifolate; Nucleoside Antimetabolite/Analog
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/denopterin.html
Solubility
10 mM in DMSO
Smiles
O=C1C2=NC(C(C)N(C3=CC=C(C=C3)C(N[C@H](C(O)=O)CCC(O)=O)=O)C)=CNC2=NC(N)=N1
Molecular Formula
C21H23N7O6
Molecular Weight
469.45
References & Citations
[1]Robert Yongxin Zhao, et al. Cross-linked pyrrolobenzodiazepine dimer (pbd) derivative and its conjugates. WO2020006722A1
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Von Hippel-Lindau (VHL)

Alternative Products

CatalogName
GTR19199319Denopterin
GTR19195915-01A-Denopterin

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