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Pyrantel

CAT: 0804-HY-12641ASize: 1 EachDry Ice: NoHazardous: No
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Description
Pyrantel is an orally active anthelmintic and an agonist of the nicotinic acetylcholine receptor (nAChR) . Pyrantel can cause spasmodic muscle paralysis in parasites. Pyrantel can be used in the study of parasitic infections such as ascariasis, hookworm infections, intestinal worms (pinworm infections), trichinosis and trichinosis[1][2].
CAS Number
15686-83-6
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
Antibiotic; nAChR; Parasite
Type
Reference compound
Related Pathways
Anti-infection; Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/pyrantel.html
Solubility
10 mM in DMSO
Smiles
CN1CCCN=C1/C=C/C2=CC=CS2
Molecular Formula
C11H14N2S
Molecular Weight
206.31
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
References & Citations
[1]Martin RJ, et al. Oxantel is an N-type (methyridine and nicotine) agonist not an L-type (levamisole and pyrantel) agonist: classification of cholinergic anthelmintics in Ascaris. Int J Parasitol. 2004 Aug;34 (9) :1083-90. |[2]Tritten L, et al. In vitro and in vivo efficacy of Monepantel (AAD 1566) against laboratory models of human intestinal nematode infections. PLoS Negl Trop Dis. 2011 Dec;5 (12) :e1457.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Launched

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