A-1210477-piperazinyl

A-1210477-piperazinyl

• CAS Number: 2351218-72-7
• UNSPSC Description: A-1210477-piperazinyl is a compound binds to protein myeloid cell leukemia 1 (MCL1) used for PROTAC technology[1].
• Target Antigen: Ligands for Target Protein for PROTAC
• Type: Reference compound
• Related Pathways: PROTAC
• Applications: Cancer-programmed cell death
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/a-1210477-piperazinyl.html
• Solubility: 10 mM in DMSO
• Smiles: O=C(C(N1CCN2CCNCC2)=C(CCCOC3=C4C=CC=CC4=CC=C3)C5=C1C(C6=C(COC7=CC=C(N8CCN(S(=O)(N(C)C)=O)CC8)C=C7)N(C)N=C6C)=CC=C5)O
• Molecular Weight: 849.05
• References & Citations: [1]Papatzimas JW, et al. From Inhibition to Degradation: Targeting the Antiapoptotic Protein Myeloid Cell Leukemia 1 (MCL1). J Med Chem. 2019 Jun 13;62(11):5522-5540.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported