Pomalidomide-amido-C4-amido-PEG2-C2-NH-Boc

Pomalidomide-amido-C4-amido-PEG2-C2-NH-Boc

• CAS Number: 2435720-04-8
• UNSPSC Description: Pomalidomide-amido-C4-amido-PEG2-C2-NH-Boc is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and 2-unit PEG linker used in PROTAC technology.
• Target Antigen: E3 Ligase Ligand-Linker Conjugates
• Type: Reference compound
• Related Pathways: PROTAC
• Applications: Cancer-programmed cell death
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/e3-ligase-ligand-linker-conjugates-53.html
• Solubility: 10 mM in DMSO
• Smiles: O=C1N(C(CC2)C(NC2=O)=O)C(C3=C1C=CC=C3NC(CCCCC(NCCOCCOCCNC(OC(C)(C)C)=O)=O)=O)=O
• Molecular Weight: 631.67
• References & Citations: [1]Wang Z, et al. Proteolysis Targeting Chimeras for the Selective Degradation of Mcl-1/Bcl-2 Derived from Nonselective Target Binding Ligands. J Med Chem. 2019 Aug 21.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported